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Endocrine Abstracts

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ea0063gp241 | Anterior and Posterior Pituitary | ECE2019

Inflammatory response to osmotic stimulus in healthy volunteers

Sailer Clara O , Wiedemann Sophia , Fenske Wiebke K , Schnyder Ingeborg , Strauss Konrad , Christ-Crain Mirjam

Context: Osmotic stimulus or stress results in release of vasopressin. Animal studies have shown that inflammatory parameters such as interleukin-6 (IL-6) and interleukin-8 (IL-8) increase in parallel, mainly in central brain regions. Whether osmotic stimulation leads to an inflammatory response in humans is unknown. We therefore investigated the influence of osmotic stimulation on the inflammatory system in healthy volunteers.Method: In this prospective...
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ea0073pep4.8 | Presented ePosters 4: Reproductive and Developmental Endocrinology | ECE2021

Current clinical practice of prenatal dexamethasone treatment in at risk pregnancies for classic 21‑hydroxylase deficiency in Europe

Nowotny Hanna F. , Blankenstein Oliver , Neumann Uta , Ahmed S. Faisal , Allen Stephanie , Baronio Federico , Battelino Tadej , Bertherat Jérôme , Bonomi Marco , de la Perrière Aude Brac , Tardy Véronique , Brucker Sara , Cappa Marco , Chanson Philippe , Bouvattier Claire , Colao Annamaria , Cools Martine , Davies Justin , Fenske Wiebke K. , Ghigo Ezio , Højbjerg Gravholt Claus , Hübner Angela , Husebye Eystein Sverre , Juul Anders , Kiefer Florian W. , Léger Juliane , Meyer Gesine , Phylactou Leonidas A. , Rohayem Julia , Russo Gianni , Scaroni Carla , Touraine Philippe , Unger Nicole , Hedi L. Claahsen-van der Grinten , Vojtková Jarmila , Yeste Diego , Günther Dörr Helmut , Lajic Svetlana , Reisch Nicole

BackgroundPrenatal dexamethasone treatment (Pdex) has been used since the 1980s to prevent virilization in female offspring suspected to have congenital adrenal hyperplasia (CAH). However, due to lack of strong evidence for its best practice as well as limited data regarding longterm adverse effects, use of dex is highly controversial. This study reveals the current medical practice regarding Pdex in female fetuses at risk of CAH due to 21hydroxylase def...
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Published by BioScientifica

Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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